tert-butyl azetidin-3-ylmethyl(methyl)carbamate

tert-butyl azetidin-3-ylmethyl(methyl)carbamate - Names and Identifiers

Name	3-(N-Boc-aminomethyl)azetidine
Synonyms	3-BOC-AMINOMETHYL-AZETIDINE 3-N-Boc-aminomethyl-azstidine 3-Boc-aminomet hylazetidineHCl 3-(N-Boc-aminomethyl)azetidine tert-butyl (azetidin-3-ylmethyl)carbamate TERT-BUTYL (AZETIDIN-3-YL) METHYLCARBAMATE 3-(N-tert-Butoxycarbonylaminomethyl)azetidine tert-butyl azetidin-3-ylmethyl(methyl)carbamate AZETIDIN-3-YLMETHYL-CARBAMIC ACID TERT-BUTYL ESTER azetidine-3-ylmethyl-carbamic acid tert-butyl ester
CAS	91188-15-7
InChI	InChI=1/C9H18N2O2.ClH/c1-9(2,3)13-8(12)7-4-11(5-7)6-10;/h7H,4-6,10H2,1-3H3;1H

tert-butyl azetidin-3-ylmethyl(methyl)carbamate - Physico-chemical Properties

Molecular Formula	C9H18N2O2
Molar Mass	186.25
Density	1.018±0.06 g/cm3(Predicted)
Boling Point	285.5±13.0 °C(Predicted)
Water Solubility	Slightly soluble in water.
pKa	12.62±0.46(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
MDL	MFCD01861760

tert-butyl azetidin-3-ylmethyl(methyl)carbamate - Risk and Safety

Hazard Class

IRRITANT

tert-butyl azetidin-3-ylmethyl(methyl)carbamate - Introduction

3-(N-Boc-aminomethyl)azetidine is an organic compound with the chemical formula C9H17NO2. It is a white crystalline solid, stable at room temperature.

The use of this compound is very wide. First, it is an important organic synthesis intermediate that can be used to synthesize other nitrogen-containing compounds. Secondly, it can be used as a raw material in research and production in the field of medicine. In addition, it can also be used for the introduction of protective groups and functional groups for organic synthesis reactions.

There are various methods for preparing 3-(N-Boc-aminomethyl)azetidine. A common method is to react n-butyl carbamate with N-tert-butoxycarbonylacetoimine (Boc2O) in the presence of sodium bicarbonate to produce 3-(N-Boc-aminomethyl)azetidine. After completion of the reaction, a pure product can also be obtained by volatilization of the solvent and crystallization.

Regarding safety information, 3-(N-Boc-aminomethyl)azetidine may be harmful to humans, and appropriate protective measures should be taken, such as wearing protective glasses and gloves, and maintaining a well-ventilated laboratory environment. At the same time, the compound should be kept away from fire and oxidizing agents, and stored in a dry, sealed container, avoid contact with air and humidity. If necessary, handle and dispose of in accordance with relevant regulations. To ensure safety, the compound should be used with detailed information and proper handling procedures should be followed.

Last Update：2024-04-09 21:11:58